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Mapping mutational effects along the evolutionary landscape of HIV envelope

Mapping mutational effects along the evolutionary landscape of HIV envelope

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071130001

Mapping mutational effects along the evolutionary landscape of HIV envelope

About this item

Full title

Mapping mutational effects along the evolutionary landscape of HIV envelope

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The immediate evolutionary space accessible to HIV is largely determined by how single amino-acid mutations affect fitness. These mutational effects can shift as the virus evolves. However, the prevalence of such shifts in mutational effects remains unclear. Here we quantify the effects on viral growth of all amino-acid mutations to two HIV envelop...

Alternative Titles

Full title

Mapping mutational effects along the evolutionary landscape of HIV envelope

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071130001

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071130001

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/235630