Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins
Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The mammalian Atg8 family proteins are central drivers of autophagy and contain six members, classified into the LC3 and GABARAP subfamilies. Due to their high sequence similarity and consequent functional overlaps, it is difficult to delineate specific functions of Atg8 proteins in autophagy. Here we discover a super-strong GABARAP-selective inhib...
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Full title
Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins
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TN_cdi_proquest_journals_2071158024
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071158024
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ISSN
1552-4450,1552-4469
E-ISSN
1552-4469
DOI
10.1038/s41589-018-0082-8
