Dazl regulates germ cell survival through a network of polyA proximal mRNA interactions
Dazl regulates germ cell survival through a network of polyA proximal mRNA interactions
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The RNA binding protein Dazl is essential for gametogenesis, but its direct in vivo functions, RNA targets, and the molecular basis for germ cell loss in DAZL null mice are unknown. Here, we mapped transcriptome-wide Dazl-RNA interactions in vivo, revealing Dazl binding to thousands of mRNAs via polyA-proximal 3UTR interactions. In parallel, fluore...
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Dazl regulates germ cell survival through a network of polyA proximal mRNA interactions
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TN_cdi_proquest_journals_2071174671
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071174671
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E-ISSN
2692-8205
DOI
10.1101/273292
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https://www.proquest.com/docview/2071174671?pq-origsite=primo&accountid=13902
