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Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in...

Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071175570

Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in cancer associated fibroblasts

About this item

Full title

Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in cancer associated fibroblasts

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The ability to disseminate, invade and successfully colonise other tissues is a critical hallmark of cancer that involves remodelling of the extracellular matrix (ECM) laid down by fibroblasts. Moreover, Cancer-Associated-Fibroblasts (CAFs) produce key growth factors and cytokines as components of the ECM that fuel tumour growth, metastasis and che...

Alternative Titles

Full title

Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in cancer associated fibroblasts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071175570

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071175570

Other Identifiers

DOI

10.1101/265884