FRI0268 Glucocorticoid-induced leucine zipper (GILZ) represents a checkpoint limiting type i interfe...
FRI0268 Glucocorticoid-induced leucine zipper (GILZ) represents a checkpoint limiting type i interferon (IFN) production in sle
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Kidlington: Elsevier Limited
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Language
English
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Kidlington: Elsevier Limited
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Contents
BackgroundGlucocorticoids (GC) remain the mainstay of treatment in Systemic Lupus Erythematosus (SLE). Type I interferons (IFN), produced by plasmacytoid dendritic cells (pDC) in response to Toll-Like receptors (TLR) ligands, are critical to SLE pathogenesis, but are not suppressed by GC. Glucocorticoid-Induced Leucine Zipper (GILZ) is an endogenou...
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Full title
FRI0268 Glucocorticoid-induced leucine zipper (GILZ) represents a checkpoint limiting type i interferon (IFN) production in sle
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TN_cdi_proquest_journals_2071187832
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071187832
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2018-eular.1847
