Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis
Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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We investigated in vitro and in vivo the pro-fibrotic role of exosomes released by muscle-derived fibroblasts of Duchenne muscular dystrophy (DMD) patients, and of miRNAs carried by exosomes. We found that exosomes from DMD fibroblasts, but not from myoblasts, had significantly higher levels of miR-199a-5p, a miRNA up-regulated in fibrotic conditio...
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Full title
Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis
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TN_cdi_proquest_journals_2071188420
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071188420
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E-ISSN
2692-8205
DOI
10.1101/267963
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https://www.proquest.com/docview/2071188420?pq-origsite=primo&accountid=13902
