AB0165 Rank/rank-ligand interaction regulates pathogenic t cell recruitment in sjögren’s syndrome
AB0165 Rank/rank-ligand interaction regulates pathogenic t cell recruitment in sjögren’s syndrome
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Nayar, S. , Fisher, B.A. , Campos, J. , Gardner, D.H. , Dumusc, A. , Iannizzotto, V. , Smith, C. , Buckley, C.D. , Bowman, S.J. , Mueller, C.G. and Barone, F.
Publisher
Kidlington: Elsevier Limited
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English
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Kidlington: Elsevier Limited
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BackgroundThe RANKL (ligand)-RANK-OPG triad, members of the TNF(R) superfamily, is implicated in lymphoid organ development and bone homeostasis. It has recently been demonstrated that RANK-activated astrocytes release CCL20 and attract T cells to the central nervous system in a model of Multiple Sclerosis and that transgenic RANK expression in the...
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AB0165 Rank/rank-ligand interaction regulates pathogenic t cell recruitment in sjögren’s syndrome
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TN_cdi_proquest_journals_2071192867
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071192867
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ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2018-eular.6563