GWAS of epigenetic ageing rates in blood reveals a critical role for TERT
GWAS of epigenetic ageing rates in blood reveals a critical role for TERT
About this item
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Author / Creator
Lu, Ake T , Xue, Luting , Salfati, Elias L , Chen, Brian H , Ferrucci, Luigi , Levy, Daniel , Joehanes, Roby , Murabito, Joanne M , Kiel, Douglas P , Pei-Chien Tsai , Yet, Idil , Bell, Jordana T , Mangino, Massimo , Tanaka, Toshiko , Mcrae, Allan , Marioni, Riccardo E , Visscher, Peter M , Wray, Naomi R , Deary, Ian J , Levine, Morgan E , Quach, Austin , Assimes, Themistocles L , Tsao, Philip S , Absher, Devin , Stewart, James D , Li, Yun , Reiner, Alex P , Hou, Lifang , Baccarelli, Andrea A , Whitsel, Eric A , Abraham, Aviv , Cardona, Alexia , Day, Felix R , Perry, John R B , Ong, Ken K , Raj, Kenneth , Lunetta, Kathryn L and Horvath, Steve
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
DNA methylation age is an accurate biomarker of chronological age and predicts lifespan, but its underlying molecular mechanisms are unknown. In this genome-wide association study of 9,907 individuals, we found gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and gene variants in 3 loci associated extr...
Alternative Titles
Full title
GWAS of epigenetic ageing rates in blood reveals a critical role for TERT
Authors, Artists and Contributors
Author / Creator
Xue, Luting
Salfati, Elias L
Chen, Brian H
Ferrucci, Luigi
Levy, Daniel
Joehanes, Roby
Murabito, Joanne M
Kiel, Douglas P
Pei-Chien Tsai
Yet, Idil
Bell, Jordana T
Mangino, Massimo
Tanaka, Toshiko
Mcrae, Allan
Marioni, Riccardo E
Visscher, Peter M
Wray, Naomi R
Deary, Ian J
Levine, Morgan E
Quach, Austin
Assimes, Themistocles L
Tsao, Philip S
Absher, Devin
Stewart, James D
Li, Yun
Reiner, Alex P
Hou, Lifang
Baccarelli, Andrea A
Whitsel, Eric A
Abraham, Aviv
Cardona, Alexia
Day, Felix R
Perry, John R B
Ong, Ken K
Raj, Kenneth
Lunetta, Kathryn L
Horvath, Steve
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2071236802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071236802
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/157776
How to access this item
https://www.proquest.com/docview/2071236802?pq-origsite=primo&accountid=13902
