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A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071246576

A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

About this item

Full title

A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Higher order chromatin structure and DNA methylation are implicated in multiple developmental processes, but their relationship to cell state is unknown. Here, we found that large (~10kb) DNA methylation nadirs can form long loops connecting anchor loci that may be dozens of megabases apart, as well as interchromosomal links. The interacting loci c...

Alternative Titles

Full title

A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071246576

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071246576

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/212928