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Accurate design of translational output by a neural network model of ribosome distribution

Accurate design of translational output by a neural network model of ribosome distribution

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071253982

Accurate design of translational output by a neural network model of ribosome distribution

About this item

Full title

Accurate design of translational output by a neural network model of ribosome distribution

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Synonymous codon choice can have dramatic effects on ribosome speed, RNA stability, and protein expression. Ribosome profiling experiments have underscored that ribosomes do not move uniformly along mRNAs, exposing a need for models of coding sequences that capture the full range of empirically observed variation. We present a method, I nos, that m...

Alternative Titles

Full title

Accurate design of translational output by a neural network model of ribosome distribution

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2071253982

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071253982

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/201517