Accurate design of translational output by a neural network model of ribosome distribution
Accurate design of translational output by a neural network model of ribosome distribution
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Synonymous codon choice can have dramatic effects on ribosome speed, RNA stability, and protein expression. Ribosome profiling experiments have underscored that ribosomes do not move uniformly along mRNAs, exposing a need for models of coding sequences that capture the full range of empirically observed variation. We present a method, I nos, that m...
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Accurate design of translational output by a neural network model of ribosome distribution
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TN_cdi_proquest_journals_2071253982
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2071253982
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E-ISSN
2692-8205
DOI
10.1101/201517
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https://www.proquest.com/docview/2071253982?pq-origsite=primo&accountid=13902