A Virus-Packageable CRISPR Screen Identifies Host Factors Mediating Interferon Inhibition of HIV
A Virus-Packageable CRISPR Screen Identifies Host Factors Mediating Interferon Inhibition of HIV
About this item
Full title
Author / Creator
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Interferon (IFN) inhibits HIV replication by inducing an array of antiviral effectors. Here we describe a novel CRISPR knockout screening approach to identify the ensemble of these HIV restriction factors. We assembled a CRISPR sgRNA library specific for Interferon Stimulated Genes (ISGs) into a modified lentiviral vector that allows for packaging...
Alternative Titles
Full title
A Virus-Packageable CRISPR Screen Identifies Host Factors Mediating Interferon Inhibition of HIV
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2072558681
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2072558681
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/363432
How to access this item
https://www.proquest.com/docview/2072558681?pq-origsite=primo&accountid=13902
