APP-induced patterned neurodegeneration exacerbated by APOE4 in C. elegans
APP-induced patterned neurodegeneration exacerbated by APOE4 in C. elegans
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Genetic and epidemiological studies have found that variations in the amyloid precursor protein (APP) and the apoliopoprotein E (APOE) genes represent major modifiers of the progressive neurodegeneration in Alzheimer's disease (AD). An extra copy or gain-of-function mutations in APP lower age of AD onset. Compared to the other isoforms (APOE3 and A...
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Full title
APP-induced patterned neurodegeneration exacerbated by APOE4 in C. elegans
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TN_cdi_proquest_journals_2075147892
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2075147892
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E-ISSN
2692-8205
DOI
10.1101/376095
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https://www.proquest.com/docview/2075147892?pq-origsite=primo&accountid=13902
