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Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infect...

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infect...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2076578258

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

About this item

Full title

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The emergence of drug resistance in avian influenza virus (AIV) is a serious concern for public health. Neuraminidase (NA) isolated from a fatal case of avian-origin H10N8 influenza virus infection was found to carry a drug-resistant mutation, NA-Arg292Lys (291 in N8 numbering). In order to understand the full potential of H10N8 drug resistance, th...

Alternative Titles

Full title

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2076578258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2076578258

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/378075