Reducing assembly complexity of microbial genomes with single-molecule sequencing
Reducing assembly complexity of microbial genomes with single-molecule sequencing
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Ithaca: Cornell University Library, arXiv.org
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English
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Ithaca: Cornell University Library, arXiv.org
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Background: The short reads output by first- and second-generation DNA sequencing instruments cannot completely reconstruct microbial chromosomes. Therefore, most genomes have been left unfinished due to the significant resources required to manually close gaps in draft assemblies. Third-generation, single-molecule sequencing addresses this problem...
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Full title
Reducing assembly complexity of microbial genomes with single-molecule sequencing
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TN_cdi_proquest_journals_2086133093
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2086133093
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E-ISSN
2331-8422
DOI
10.48550/arxiv.1304.3752
