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Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2090916863

Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

About this item

Full title

Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Subjects

More information

Scope and Contents

Contents

Cell-free transcription-translation systems have great potential for biosensing, yet the range of detectable chemicals is limited. Here we provide a framework to expand the range of molecules detectable by cell-free biosensors by combining synthetic metabolic cascades with transcription factor-based networks. These hybrid cell-free biosensors are h...

Alternative Titles

Full title

Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2090916863

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2090916863

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/397315