Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and G...
Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and Gene Expression
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Iron and heme play central roles in red blood cell production. However, the mechanisms by which iron and heme levels coordinate erythropoiesis remain incompletely understood. HRI is a heme-regulated kinase that controls translation by phosphorylating eIF2 . Here, we investigate the global impact of iron, heme and HRI on protein translation in vivo...
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Full title
Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and Gene Expression
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TN_cdi_proquest_journals_2099218611
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2099218611
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E-ISSN
2692-8205
DOI
10.1101/408054
How to access this item
https://www.proquest.com/docview/2099218611?pq-origsite=primo&accountid=13902
