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Physical interaction of junctophilin and the Ca^sub V^1.1 C terminus is crucial for skeletal muscle...

Physical interaction of junctophilin and the Ca^sub V^1.1 C terminus is crucial for skeletal muscle...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2099973175

Physical interaction of junctophilin and the Ca^sub V^1.1 C terminus is crucial for skeletal muscle contraction

About this item

Full title

Physical interaction of junctophilin and the Ca^sub V^1.1 C terminus is crucial for skeletal muscle contraction

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (17), p.4507

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Close physical association of CaV1.1 L-type calcium channels (LTCCs) at the sarcolemmal junctional membrane (JM) with ryanodine receptors (RyRs) of the sarcoplasmic reticulum (SR) is crucial for excitation–contraction coupling (ECC) in skeletal muscle. However, the molecular mechanism underlying the JM targeting of LTCCs is unexplored. Junctophilin...

Alternative Titles

Full title

Physical interaction of junctophilin and the Ca^sub V^1.1 C terminus is crucial for skeletal muscle contraction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2099973175

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2099973175

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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