Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodys...
Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia
About this item
Full title
Author / Creator
Shiozawa, Yusuke , Malcovati, Luca , Gallì, Anna , Sato-Otsubo, Aiko , Kataoka, Keisuke , Sato, Yusuke , Watatani, Yosaku , Suzuki, Hiromichi , Yoshizato, Tetsuichi , Yoshida, Kenichi , Sanada, Masashi , Makishima, Hideki , Shiraishi, Yuichi , Chiba, Kenichi , Hellström-Lindberg, Eva , Miyano, Satoru , Ogawa, Seishi and Cazzola, Mario
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Spliceosome mutations are frequently found in myelodysplasia. Splicing alterations induced by these mutations, their precise targets, and the effect at the transcript level have not been fully elucidated. Here we report transcriptomic analyses of 265 bone marrow samples from myelodysplasia patients, followed by a validation using CRISPR/Cas9-mediat...
Alternative Titles
Full title
Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia
Authors, Artists and Contributors
Author / Creator
Malcovati, Luca
Gallì, Anna
Sato-Otsubo, Aiko
Kataoka, Keisuke
Sato, Yusuke
Watatani, Yosaku
Suzuki, Hiromichi
Yoshizato, Tetsuichi
Yoshida, Kenichi
Sanada, Masashi
Makishima, Hideki
Shiraishi, Yuichi
Chiba, Kenichi
Hellström-Lindberg, Eva
Miyano, Satoru
Ogawa, Seishi
Cazzola, Mario
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2100849146
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2100849146
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06063-x
