Log in to save to my catalogue

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP^...

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP^...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2101981474

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP^sub 2^ depletion

About this item

Full title

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP^sub 2^ depletion

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.E3569

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Brain capillaries play a critical role in sensing neural activity and translating it into dynamic changes in cerebral blood flow to serve the metabolic needs of the brain. The molecular cornerstone of this mechanism is the capillary endothelial cell inward rectifier K+ (Kir2.1) channel, which is activated by neuronal activity–dependent increases in...

Alternative Titles

Full title

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP^sub 2^ depletion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2101981474

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2101981474

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

How to access this item