Ligand modulation of allosteric networks in an ancestral steroid receptor
Ligand modulation of allosteric networks in an ancestral steroid receptor
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Understanding the evolution of binding specificity, a heavily studied area of research, is key for determining how protein sequence changes alter function. Ligand-activation in the steroid receptor subfamily of transcription factors operates via a common allosteric mechanism which permits extant receptors to respond specifically to their cognate ho...
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Full title
Ligand modulation of allosteric networks in an ancestral steroid receptor
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TN_cdi_proquest_journals_2102157492
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2102157492
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E-ISSN
2692-8205
DOI
10.1101/414375
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https://www.proquest.com/docview/2102157492?pq-origsite=primo&accountid=13902