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Ligand modulation of allosteric networks in an ancestral steroid receptor

Ligand modulation of allosteric networks in an ancestral steroid receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2102157492

Ligand modulation of allosteric networks in an ancestral steroid receptor

About this item

Full title

Ligand modulation of allosteric networks in an ancestral steroid receptor

Author / Creator

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Understanding the evolution of binding specificity, a heavily studied area of research, is key for determining how protein sequence changes alter function. Ligand-activation in the steroid receptor subfamily of transcription factors operates via a common allosteric mechanism which permits extant receptors to respond specifically to their cognate ho...

Alternative Titles

Full title

Ligand modulation of allosteric networks in an ancestral steroid receptor

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2102157492

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2102157492

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/414375