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Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregul...

Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_210362675

Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregulation of NF-κB in Response to Treatment with Etanercept

About this item

Full title

Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregulation of NF-κB in Response to Treatment with Etanercept

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2005-06, Vol.124 (6), p.1275-1283

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Etanercept, a recombinant human tumor necrosis factor (TNF) receptor fusion protein, is FDA approved for psoriasis and psoriatic arthritis. TNFα increases the synthesis of proinflammatory cytokines and leads to the activation of multiple signaling pathways, including nuclear factor kappa B (NF-κB). The Rel/NF-κB transcription factors play a central...

Alternative Titles

Full title

Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregulation of NF-κB in Response to Treatment with Etanercept

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_210362675

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_210362675

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1111/j.0022-202X.2005.23735.x

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