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P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na + /Ca 2+ Exchanger Expression and Activity...

P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na + /Ca 2+ Exchanger Expression and Activity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117145977

P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na + /Ca 2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes

About this item

Full title

P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na + /Ca 2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes

Publisher

Basel: S. Karger AG

Journal title

Cellular physiology and biochemistry, 2017-10, Vol.42 (6), p.2169-2181

Language

English

Formats

Publication information

Publisher

Basel: S. Karger AG

More information

Scope and Contents

Contents

Background: TGFβ1, a decisive regulator of megakaryocyte maturation and platelet formation, has previously been shown to up-regulate both, store operated Ca2+ entry (SOCE) and Ca2+ extrusion by Na+/Ca2+ exchange. The growth factor thus augments the increase of cytosolic Ca2+ activity ([Ca2+]i) following release of Ca2+ from intracellular stores and...

Alternative Titles

Full title

P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na + /Ca 2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2117145977

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117145977

Other Identifiers

ISSN

1015-8987

E-ISSN

1421-9778

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