Aldehyde Dehydrogenase-2 Attenuates Myocardial Remodeling and Contractile Dysfunction Induced by a H...
Aldehyde Dehydrogenase-2 Attenuates Myocardial Remodeling and Contractile Dysfunction Induced by a High-Fat Diet
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Author / Creator
Li, Chuanbao , Li, Xiaoxing , Chang, Ying , Zhao, Lang , Liu, Baoshan , Wei, Shujian , Xu, Feng , Zhang, Yun and Chen, Yuguo
Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Abstract
Background/Aims: Consumption of a high-fat (HF) diet exacerbates metabolic cardiomyopathy through lipotoxic mechanisms. In this study, we explored the role of aldehyde dehydrogenase-2 (ALDH2) in myocardial damage induced by a HF diet. Methods: Wild-type C57 BL/6J mice were fed a HF diet or control diet for 16 weeks. ALDH2 overexpression...
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Full title
Aldehyde Dehydrogenase-2 Attenuates Myocardial Remodeling and Contractile Dysfunction Induced by a High-Fat Diet
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TN_cdi_proquest_journals_2117195941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117195941
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000492506
