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Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct...

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117260829

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens

About this item

Full title

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Background: The D3 receptor (D3R) has emerged as a promising pharmacotherapeutic target for the treatment of several diseases including schizophrenia, Parkinsons disease, and substance use disorders. However, studies investigating the modulatory impact of D3R antagonism on dopamine neurotransmission or the effects drugs of abuse have produced mixed...

Alternative Titles

Full title

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2117260829

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117260829

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/439398