Parkin is a disease modifier in the mutant SOD 1 mouse model of ALS
Parkin is a disease modifier in the mutant SOD 1 mouse model of ALS
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Publisher
Frankfurt: EMBO Press
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Language
English
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Publisher
Frankfurt: EMBO Press
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Mutant Cu/Zn superoxide dismutase (SOD1) causes mitochondrial alterations that contribute to motor neuron demise in amyotrophic lateral sclerosis (ALS). When mitochondria are damaged, cells activate mitochondria quality control (MQC) mechanisms leading to mitophagy. Here, we show that in the spinal cord of G93A mutant SOD1 transgenic mice (SOD1‐G93...
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Full title
Parkin is a disease modifier in the mutant SOD 1 mouse model of ALS
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TN_cdi_proquest_journals_2117729245
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2117729245
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201808888
