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Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of...

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2122910454

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

About this item

Full title

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Polyglutamine (polyQ) tracts are regions of low sequence complexity of variable length found in more than one hundred human proteins. These tracts are frequent in activation domains of transcription factors and their length often correlates with transcriptional activity. In addition, in nine proteins, tract elongation beyond specific thresholds cau...

Alternative Titles

Full title

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2122910454

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2122910454

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/447896