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Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in i...

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2124761546

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis

About this item

Full title

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis

Publisher

United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins

Journal title

The American journal of gastroenterology, 2018-10, Vol.113 (10), p.1475-1483

Language

English

Formats

Publication information

Publisher

United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins

More information

Scope and Contents

Contents

Variants in patatin-like phospholipase domain-containing 3 (PNPLA3; rs738409), transmembrane 6 superfamily member 2 (TM6SF2; rs58542926), and membrane bound O-acyltransferase domain containing 7 (MBOAT7; rs641738) are risk factors for the development of alcohol-related cirrhosis. Within this population, PNPLA3 rs738409 is also an established risk f...

Alternative Titles

Full title

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2124761546

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2124761546

Other Identifiers

ISSN

0002-9270

E-ISSN

1572-0241

DOI

10.1038/s41395-018-0041-8

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