Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma
About this item
Full title
Author / Creator
Noorani, Ayesha , Goddard, Martin , Crawte, Jason , Alexandrov, Ludmil B , Li, Xiaodun , Secrier, Maria , Eldridge, Matthew D , Bower, Lawrence , Weaver, Jamie , Lao-Sirieix, Pierre , Martincorena, Inigo , Debiram-Beecham, Irene , Grehan, Nicola , Macrae, Shona , Malhotra, Shalini , Miremadi, Ahmad , Thomas, Tabitha , Galbraith, Sarah , Petersen, Lorraine , Preston, Stephen , Gilligan, David , Hindmarsh, Andrew , Hardwick, Richard , Consortium, Occams , Stratton, Michael R , Wedge, David C and Fitzgerald, Rebecca C
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Continual evolution of cancer makes it challenging to predict clinical outcomes. Highly varied and unpredictable patient outcomes in esophageal adenocarcinoma (EAC) prompted us to question the pattern and timing of metastatic spread. Whole genome sequencing and phylogenetic analysis of 396 samples across 18 EAC cases demonstrated a stellate pattern...
Alternative Titles
Full title
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma
Authors, Artists and Contributors
Author / Creator
Goddard, Martin
Crawte, Jason
Alexandrov, Ludmil B
Li, Xiaodun
Secrier, Maria
Eldridge, Matthew D
Bower, Lawrence
Weaver, Jamie
Lao-Sirieix, Pierre
Martincorena, Inigo
Debiram-Beecham, Irene
Grehan, Nicola
Macrae, Shona
Malhotra, Shalini
Miremadi, Ahmad
Thomas, Tabitha
Galbraith, Sarah
Petersen, Lorraine
Preston, Stephen
Gilligan, David
Hindmarsh, Andrew
Hardwick, Richard
Consortium, Occams
Stratton, Michael R
Wedge, David C
Fitzgerald, Rebecca C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2127074948
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2127074948
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/454306
How to access this item
https://www.proquest.com/docview/2127074948?pq-origsite=primo&accountid=13902