Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and ce...
Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Cellular senescence is triggered by diverse stimuli and is characterised by long-term growth arrest and secretion of cytokines and chemokines (termed the SASP - senescence-associated secretory phenotype). Senescence can be organismally beneficial as it can prevent the propagation of damaged or mutated clones and stimulate their clearance by immune...
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Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence
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TN_cdi_proquest_journals_2131015367
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2131015367
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2692-8205
DOI
10.1101/463851
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https://www.proquest.com/docview/2131015367?pq-origsite=primo&accountid=13902