Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects
Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects
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Publisher
Berlin: Springer
Journal title
Language
English
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Publisher
Berlin: Springer
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Contents
The study under discussion was a drug-drug interaction study in which the effect of ketoconazole, a potent CYP450 3A4 inhibitor, on the pharmacokinetics of Glivec (imatinib) was investigated. A total of 14 healthy subjects (13 male, 1 female) were enrolled in this study. Each subject received a single oral dose of imatinib 200 mg alone, and a singl...
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Full title
Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects
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TN_cdi_proquest_journals_213516208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213516208
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-004-0832-z
