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Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cel...

Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213527100

Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer

About this item

Full title

Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer

Publisher

Berlin: Springer

Journal title

Cancer chemotherapy and pharmacology, 2003-04, Vol.51 (4), p.328-336

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

Gemcitabine administered at a fixed dose rate of 10 mg/m(2) per min has been reported to achieve plasma steady-state concentrations ranging from 10 to 20 microM in patients with acute leukemia. These concentrations have been shown to saturate the intracellular accumulation of the active triphosphate metabolite. We designed this pharmacokinetic stud...

Alternative Titles

Full title

Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_213527100

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213527100

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-002-0560-1

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