Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes
Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
To assess the in vivo release profile and the retinal toxicity of a poly (lactic-co-glycolic acid) (PLGA) sustained-release sirolimus (SRL) intravitreal implant in normal rabbit eyes.
Methods
PLGA intravitreal implants containing or not SRL were prepared, and the viability of ARPE-19 and hES-RPE human retinal cell lines was examine...
Alternative Titles
Full title
Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_2135410410
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2135410410
Other Identifiers
ISSN
0012-4486
E-ISSN
1573-2622
DOI
10.1007/s10633-018-9664-8
