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Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant...

Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2138057084

Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

About this item

Full title

Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2018-11, Vol.9 (12), p.1164-13, Article 1164

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by carbon tetrachloride (CCl
4
) in a murine model and the underlying molecular mechanisms. Ninety-six mice were randomly divided into the control (
n
 = 8), CQ (
n
 = 8), CCl
4
(
n
 = 40), and CCl
4
 + CQ (
n...

Alternative Titles

Full title

Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2138057084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2138057084

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-018-1136-2

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