Erk 1,2 phosphorylates p27Kip1: Functional evidence for a role in high glucose-induced hypertrophy o...
Erk 1,2 phosphorylates p27Kip1: Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells
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Author / Creator
WOLF, G , REINKING, R , ZAHNER, G , STAHL, R. A. K and SHANKLAND, S. J
Publisher
Berlin: Springer
Journal title
Language
English
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Publication information
Publisher
Berlin: Springer
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Scope and Contents
Contents
Mesangial cell hypertrophy is one of the earliest morphological abnormalities of diabetic nephropathy. We have previously shown that high glucose induces p27(Kip1) by a post-transcriptional mechanism and that mesangial cell hypertrophy depends on G(1)-phase arrest mediated by this CDK-inhibitor. However, it remains poorly understood how high glucos...
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Full title
Erk 1,2 phosphorylates p27Kip1: Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_213855153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213855153
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-003-1163-z
