Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-...
Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-Galactosidase
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Publisher
Washington: Am Assoc Clin Chem
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Language
English
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Publisher
Washington: Am Assoc Clin Chem
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Contents
The determination of cellular β-galactocerebrosidase activity is an established procedure to diagnose Krabbe disease and monitor the efficacy of gene/stem cell-based therapeutic approaches aimed at restoring defective enzymatic activity in patients or disease models. Current biochemical assays for β-galactocerebrosidase show high specificity but ge...
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Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-Galactosidase
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TN_cdi_proquest_journals_213984339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213984339
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ISSN
0009-9147
E-ISSN
1530-8561
DOI
10.1373/clinchem.2008.115873