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Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-...

Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213984339

Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-Galactosidase

About this item

Full title

Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-Galactosidase

Publisher

Washington: Am Assoc Clin Chem

Journal title

Clinical chemistry (Baltimore, Md.), 2009-03, Vol.55 (3), p.541

Language

English

Formats

Publication information

Publisher

Washington: Am Assoc Clin Chem

More information

Scope and Contents

Contents

The determination of cellular β-galactocerebrosidase activity is an established procedure to diagnose Krabbe disease and monitor the efficacy of gene/stem cell-based therapeutic approaches aimed at restoring defective enzymatic activity in patients or disease models. Current biochemical assays for β-galactocerebrosidase show high specificity but ge...

Alternative Titles

Full title

Specific Determination of {beta}-Galactocerebrosidase Activity via Competitive Inhibition of {beta}-Galactosidase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_213984339

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_213984339

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1373/clinchem.2008.115873

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