Oral administration of a low dose of midazolam (75 μg) as an in vivo probe for CYP3A activity
Oral administration of a low dose of midazolam (75 μg) as an in vivo probe for CYP3A activity
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Publisher
Heidelberg: Springer
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Language
English
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Heidelberg: Springer
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We investigated whether the oral administration of a low dose (75 micro g) of midazolam, a CYP3A probe, can be used to measure the in vivo CYP3A activity.
Plasma concentrations of midazolam, 1'OH-midazolam and 4'OH-midazolam were measured after the oral administration of 7.5 mg and 75 micro g midazolam in 13 healthy subjects without medication,...
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Full title
Oral administration of a low dose of midazolam (75 μg) as an in vivo probe for CYP3A activity
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TN_cdi_proquest_journals_214477738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_214477738
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ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-004-0762-z
