Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population:...
Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population: impact of age
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Publisher
Heidelberg: Springer
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Language
English
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Publisher
Heidelberg: Springer
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Contents
Thiopurine drugs are commonly used in pediatric patients for the treatment of acute leukemia, organ transplantation and inflammatory diseases. They are catabolized by the cytosolic thiopurine methyltransferase (TPMT), which is subject to a genetic polymorphism. In children, enzyme activities are immature at birth and developmental patterns vary wid...
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Full title
Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population: impact of age
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TN_cdi_proquest_journals_214477978
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_214477978
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ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-004-0732-5
