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Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Tr...

Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Tr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2149615925

Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Trials in Patients with Coronary Artery Disease

About this item

Full title

Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Trials in Patients with Coronary Artery Disease

Publisher

Cham: Springer International Publishing

Journal title

American journal of cardiovascular drugs : drugs, devices, and other interventions, 2018-04, Vol.18 (2), p.109-115

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background
Inhibition of bromodomain and extra-terminal (BET) proteins can modulate lipoprotein and inflammatory factors that mediate atherosclerosis. The impact of the BET inhibitor, apabetalone, on cardiovascular events is unknown.
Objective
Our objective was to investigate the impact of apabetalone on cardiovascular event rates in a poo...

Alternative Titles

Full title

Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Trials in Patients with Coronary Artery Disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2149615925

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2149615925

Other Identifiers

ISSN

1175-3277

E-ISSN

1179-187X

DOI

10.1007/s40256-017-0250-3

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