A malaria vaccine adjuvant based on recombinant antigen binding to liposomes
A malaria vaccine adjuvant based on recombinant antigen binding to liposomes
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pfs25 is a malaria transmission-blocking vaccine antigen candidate, but its apparently limited immunogenicity in humans has hindered clinical development. Here, we show that recombinant, polyhistidine-tagged (his-tagged) Pfs25 can be mixed at the time of immunization with pre-formed liposomes containing cobalt porphyrin–phospholipid, resulting in s...
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Full title
A malaria vaccine adjuvant based on recombinant antigen binding to liposomes
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TN_cdi_proquest_journals_2151198839
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2151198839
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-018-0271-3
