Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients w...
Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
About this item
Full title
Author / Creator
Pollyea, Daniel A. , Stevens, Brett M. , Jones, Courtney L. , Winters, Amanda , Pei, Shanshan , Minhajuddin, Mohammad , D’Alessandro, Angelo , Culp-Hill, Rachel , Riemondy, Kent A. , Gillen, Austin E. , Hesselberth, Jay R. , Abbott, Diana , Schatz, Derek , Gutman, Jonathan A. , Purev, Enkhtsetseg , Smith, Clayton and Jordan, Craig T.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Leukemia stem cells (LSCs) drive the initiation and perpetuation of AML, are quantifiably associated with worse clinical outcomes, and often persist after conventional chemotherapy resulting in relapse
1
–
5
. In this report, we show that treatment of older patien...
Alternative Titles
Full title
Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
Authors, Artists and Contributors
Author / Creator
Stevens, Brett M.
Jones, Courtney L.
Winters, Amanda
Pei, Shanshan
Minhajuddin, Mohammad
D’Alessandro, Angelo
Culp-Hill, Rachel
Riemondy, Kent A.
Gillen, Austin E.
Hesselberth, Jay R.
Abbott, Diana
Schatz, Derek
Gutman, Jonathan A.
Purev, Enkhtsetseg
Smith, Clayton
Jordan, Craig T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2151203372
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2151203372
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0233-1
