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Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlation...

Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2154899482

Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms

About this item

Full title

Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2019-03, Vol.83 (3), p.493-500

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
This study investigated correlations of the clinical outcomes of oral metronomic vinorelbine (VNR) with VNR pharmacokinetics and MDR1 polymorphisms.
Methods
Eighty-two patients with metastatic non-small cell lung cancer (NSCLC) unfit for standard chemotherapy were treated with VNR at the oral doses of 20–30 mg every other day or 50...

Alternative Titles

Full title

Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2154899482

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2154899482

Other Identifiers

ISSN

0344-5704,1432-0843

E-ISSN

1432-0843

DOI

10.1007/s00280-018-3751-0

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