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Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages

Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2160700798

Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages

About this item

Full title

Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages

Publisher

Greece: Spandidos Publications

Journal title

Molecular medicine reports, 2019-01, Vol.19 (1), p.629-637

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

Lactate is an important metabolite in cellular metabolism and fluctuates in certain disease conditions including cancer and immune diseases. It was hypothesized that a decrease in lactate would modulate the inflammatory response elicited by lipopolysaccharides (LPS) in macrophages. When RAW 264.7 macrophages were treated with FX11, a specific lacta...

Alternative Titles

Full title

Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2160700798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2160700798

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2018.9678

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