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The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2162906078

The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

About this item

Full title

The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Mammalian cells express multiple 2-oxoglutarate (OG)-dependent dioxygenases, including many chromatin regulators. The oxygen affinities, and hence oxygen sensing capabilities, of the 2-oxoglutarate (OG)-dependent dioxygenases reported to date vary widely. Hypoxia can affect chromatin, but whether this reflects a direct effect on chromatin-modifying...

Alternative Titles

Full title

The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2162906078

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2162906078

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/510479

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