Experimental NIDDM : Development of a new model in adult rats administered streptozotocin and nicoti...
Experimental NIDDM : Development of a new model in adult rats administered streptozotocin and nicotinamide
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Author / Creator
MASIELLO, P , BROCA, C , GROSS, R , ROYE, M , MANTEGHETTI, M , HILLAIRE-BUYS, D , NOVELLI, M and RIBES, G
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
We took advantage of the partial protection exerted by suitable dosages of nicotinamide against the beta-cytotoxic effect of streptozotocin (STZ) to create a new experimental diabetic syndrome in adult rats that appears closer to NIDDM than other available animal models with regard to insulin responsiveness to glucose and sulfonylureas. Among the v...
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Full title
Experimental NIDDM : Development of a new model in adult rats administered streptozotocin and nicotinamide
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Record Identifier
TN_cdi_proquest_journals_216459797
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_216459797
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ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/diab.47.2.224