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Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation requi...

Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation requi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2166616800

Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation require Lysine Specific Demethylase (LSD)1-dependent recruitment of the BHC complex

About this item

Full title

Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation require Lysine Specific Demethylase (LSD)1-dependent recruitment of the BHC complex

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Growth Factor Independence (GFI)1B coordinates assembly of transcriptional repressor complexes comprised of co-repressors and histone modifying enzymes to control gene expression programs governing lineage allocation in hematopoiesis. Enforced expression of GFI1B in K562 erythroleukemia cells favors erythroid over megakaryocytic differentiation, pr...

Alternative Titles

Full title

Growth Factor Independence (GFI) 1B-mediated transcriptional repression and lineage allocation require Lysine Specific Demethylase (LSD)1-dependent recruitment of the BHC complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2166616800

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2166616800

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/519090