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Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Sm...

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Sm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_217175345

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-[beta] pathway - implication of C-Krox and Sp1

About this item

Full title

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-[beta] pathway - implication of C-Krox and Sp1

Publisher

Bucharest: Blackwell Publishing Ltd

Journal title

Journal of cellular and molecular medicine, 2008-12, Vol.12 (6b), p.2836

Language

English

Formats

Publication information

Publisher

Bucharest: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Despite several investigations, the transcriptional mechanisms which regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either physiological or pathological situations, such as scleroderma, are not completely known. In this study, we determined the effects of both native ichtyan chondroitin sulphate (CS) and its derived hy...

Alternative Titles

Full title

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-[beta] pathway - implication of C-Krox and Sp1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_217175345

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_217175345

Other Identifiers

ISSN

1582-1838

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