Reduced ligand affinity leads to an impaired function of the adenosine A^sub 2A^ receptor of human g...
Reduced ligand affinity leads to an impaired function of the adenosine A^sub 2A^ receptor of human granulocytes in sepsis
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Bucharest: Blackwell Publishing Ltd
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English
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Bucharest: Blackwell Publishing Ltd
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The enhanced release of reactive oxygen species by excessively activated polymorphonuclear leucocytes (PMN) is a key step in the pathogenesis of sepsis. Potent action of adenosine in inhibiting cytotoxic PMN functions has been documented. Recent data, however provide evidence that in sepsis a diminished capability of adenosine to inhibit the genera...
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Reduced ligand affinity leads to an impaired function of the adenosine A^sub 2A^ receptor of human granulocytes in sepsis
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TN_cdi_proquest_journals_217182875
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_217182875
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ISSN
1582-1838
