Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer
Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer
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Author / Creator
Corona, Rosario I , Ji-Heui Seo , Lin, Xianzhi , Hazelett, Dennis J , Reddy, Jessica , ough Abassi , Lin, Yvonne G , Mhawech-Fauceglia, Paulette Y , Lester, Jenny , Shah, Sohrab P , Huntsman, David G , Gusev, Alexander , Karlan, Beth Y , Berman, Benjamin P , Freedman, Matthew L , Gayther, Simon A and Lawrenson, Kate
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Transcriptional regulation is highly disease and cell-type specific. We performed H3K27ac chromatin immunoprecipitation and transcriptomic sequencing in primary tumors for the four different subtypes of invasive epithelial ovarian cancer (OC). Histotype-specific regulatory elements (REs) were enriched in enhancers (P<0.001). In silico prediction of...
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Full title
Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer
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TN_cdi_proquest_journals_2174586102
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2174586102
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E-ISSN
2692-8205
DOI
10.1101/537886
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https://www.proquest.com/docview/2174586102?pq-origsite=primo&accountid=13902
