Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells
Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells
About this item
Full title
Author / Creator
Polak, Marta E , Sirvent, Sofia , Clayton, Kalum , Davies, James D , Vallejo, Andres F , Wu, Zhiguo , Woo, Jeongmin , Riddell, Jeremy , Stumpf, Patrick S , Rose-Zerilli, Matthew , West, Jonathan , Pujato, Mario , Chen, Xiaoting , Woelk, Christopher H , Macarthur, Benjamin D , Ardern-Jones, Michael R , Friedmanm, Peter S , Weirauch, Matthew and Singh, Harinder
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Langerhans cells (LCs) in the epidermis present MHC I and MHC II-restricted antigens thereby priming either CD8 or CD4 T cell immune responses. The genomic programs and transcription factors regulating antigen presentation in LCs remain to be elucidated. We show human LCs are highly efficient in MHC I-antigen cross-presentation but lack the transcr...
Alternative Titles
Full title
Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells
Authors, Artists and Contributors
Author / Creator
Sirvent, Sofia
Clayton, Kalum
Davies, James D
Vallejo, Andres F
Wu, Zhiguo
Woo, Jeongmin
Riddell, Jeremy
Stumpf, Patrick S
Rose-Zerilli, Matthew
West, Jonathan
Pujato, Mario
Chen, Xiaoting
Woelk, Christopher H
Macarthur, Benjamin D
Ardern-Jones, Michael R
Friedmanm, Peter S
Weirauch, Matthew
Singh, Harinder
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2176093131
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2176093131
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/541383
How to access this item
https://www.proquest.com/docview/2176093131?pq-origsite=primo&accountid=13902
