Design and evaluation of novel 4-anilinoquinolines and quinazolines as EGFR inhibitors in lung cance...
Design and evaluation of novel 4-anilinoquinolines and quinazolines as EGFR inhibitors in lung cancer and chordoma
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Epidermal growth factor receptor (EGFR) inhibitors have been used to target non-small cell lung cancer (NSCLC) and chordomas with varying amounts of success. We have probed several key structural features including an interaction with Asp855 within the EGFR DGF motif and interactions with the active site water network. The EGFR target engagement wa...
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Design and evaluation of novel 4-anilinoquinolines and quinazolines as EGFR inhibitors in lung cancer and chordoma
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TN_cdi_proquest_journals_2178453663
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2178453663
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E-ISSN
2692-8205
DOI
10.1101/545525
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https://www.proquest.com/docview/2178453663?pq-origsite=primo&accountid=13902
